Sweeteners and the Gut Microbiome: Effects on Gastrointestinal Cancers

Worldwide, the demand for natural and synthetic sweeteners in food industry as an alternative to refined sugar is increasing. This has prompted more research be conducted estimate its safety effects on health. The gut microbiome critical metabolizing selected which might affect overall Recently, studies have evaluated relationship between microbiome. review summarizes current knowledge regarding role played by sweeteners. It also addresses influence of five their metabolites GI cancer-related pathways. Overall, observed positive sweetener consumption cancer pathways, such apoptosis cell cycle arrest, require further investigation order understand underlying mechanism.